Panic disorder is a condition characterized by recurrent, unprovoked attacks of extreme anxiety. Despite considerable research suggesting a neurobiological component in the etiology of panic disorder, the mechanisms of its pathogenesis remain uncertain. The exaggerated lactic acid response to alkalosis, which has been consistently observed in panic disorder, may provide an important clue to the pathogenesis of this illness. This article examines the possible mechanisms of this exaggerated lactic acid response and how they may contribute to the underlying pathophysiology of panic disorder.
Updated on June 7, 2020